OCG19
The only solution to analyze breathing-enhanced Oxygen-Sensitive CMR
AI-Powered Coronary Vascular Function Testing
Unlocking the Unprecedented Biomarkers From Oxygenation-Sensitive Cardiac Magnetic Resonance with Area19’s OCG19
Fast
3 minute aquisition time
Effortless
Stress Free Testing of Coronary Vascular Function
Available
Adapted Standard CMR Sequence (SSFP)
No Radiation
No Needles
No Stress
High-Resolution AI-Informed Analysis
High Spatial Resolution
High Temporal Resolution
Simultaneous assesment of ventricular function
Signature Biomarkers
(time-resolved myocardial oxygenation profile)
Offering simultaneous assessment of ventricular function.
No Contrast Agent
Oxygenation-Sensitive Cardiovascular Magnetic Resonance (OS-CMR) can be used to track tissue oxygenation in quasi-real-time.
No Pharmacological or Physical Stress
In the heart and the brain, hyperventilation decreases blood flow, while breath-holding increases it. The associated changes in tissue oxygenation can be tracked by OS-CMR and OCG19.
Breath Hold
Personalized Risk Stratification
The response of the vascular system to the breathing maneuver can be tracked across the cardiac cycle (OxyCardioGram – OCG) and throughout vasoactive breathing maneuvers. The analysis yields an individual response profile and multiple biomarkers for coronary macro- and microvascular function.
Hillier E. & Friedrich MG. JoVE, 2022.
Coronary Vascular Health Screening One of a kind
The only non-invasive imaging technique that assesses coronary vascular function through the responsiveness to a vasoactive breathing maneuver (5).
Due to the fast, easy, and safe scan protocol, it is ideal for coronary vascular health screening in various clinical settings.
Detecting Early Disease for Informing Preventive Action
OS-CMR paves the way for personalized cardiovascular prevention by identifying endothelial dysfunction as the earliest sign of atherosclerosis. Detecting disease onset enables early, personalized interventions such as lifestyle modifications or medication that can add quality-adjusted life years (QALY).
OS-CMR and OCG19
OS-CMR images are analyzed using the proprietary Area19 technology. Several biomarkers are extracted from thousands of data points. The resulting markers can provide a clear picture of the vascular status of the heart.
Dynamic Updates
OS-CMR Images are analyzed using the proprietary Area19 technology. Several biomarkers are extracted from thousands of data points
Dynamic Updates
OS-CMR Images are analyzed using the proprietary Area19 technology. Several biomarkers are extracted from thousands of data points
Dynamic Updates
OS-CMR Images are analyzed using the proprietary Area19 technology. Several biomarkers are extracted from thousands of data points
Integration of Breathing-Enhanced OS-CMR in Clinical Routine
CMR is the most versatile advanced cardiac imaging modality, with quantitative information on cardiac morphology, function, and tissue pathology. Additional coronary vascular function testing further augments the value and sets the stage for a short, ultra-efficient diagnostic procedure.
OS-CMR + OCG19
Safe. Convenient. Just Better.
FAQ for Oxygenation CMR
Answer: Yes, if your technologist has a basic understanding of cardiac MR, they should have no difficulty running the scan.